CD86 Rabbit Polyclonal Antibody (CAB16805)
- SKU:
- CAB16805
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | CD86 Rabbit Polyclonal Antibody |
SKU: | CAB16805 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-133 of human CD86 (NP_787058.4). |
Sequence: | PLKI QAYF NETA DLPC QFAN SQNQ SLSE LVVF WQDQ ENLV LNEV YLGK EKFD SVHS KYMG RTSF DSDS WTLR LHNL QIKD KGLY QCII HHKK PTGM IRIH QMNS ELSV L |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | B70; B7-2; B7.2; LAB72; CD28LG2; CD86 |
Positive Sample: | Raji,Mouse thymus,Rat thymus |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 38kDa |
Observed MW: | 65-70kDa |
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 942 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |