The CD86 Rabbit Monoclonal Antibody (CAB19026) offered by Assay Genie is a valuable tool for researchers studying CD86, another important cell surface molecule involved in immune regulation. This antibody, also raised in rabbits, displays high reactivity with human samples and is validated for use in various applications, including Western blotting.CD86, also known as B7-2, plays a key role in T cell activation and immune response regulation. By binding to CD86, researchers can gain valuable insights into the function and expression of this critical protein in different cell types.
This makes the CD86 Rabbit Monoclonal Antibody ideal for studies in immunology, autoimmune disorders, and other areas where CD86 is implicated in disease pathology.By utilizing this antibody in research, scientists can further our understanding of the role CD86 plays in immune regulation, paving the way for potentially groundbreaking discoveries and the development of targeted therapies for a range of diseases.
Product Name:
CD86 Rabbit Monoclonal Antibody
SKU:
CAB19026
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CD86 (P42081).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
38kDa
Observed MW:
80kDa
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
942
Clone Number:
ARC0333
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CD86 antibody (CAB19026) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
