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CD86 Monoclonal Antibody, FITC [mB7-2] (CPAB0369)

SKU:
CPAB0369
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a
Clone:
mB7-2
$792
Frequently bought together:

Description

system_update_alt Datasheet

CD86 Monoclonal Antibody, FITC [mB7-2] (CPAB0369)

The CD86 Antibody (FITC) (CPAB0369) is a valuable tool for research involving CD86, a key co-stimulatory molecule involved in immune activation and regulation. This polyclonal antibody, produced in rabbits, is highly specific and reactive with human samples, making it an ideal choice for various experimental applications.CD86, also known as B7-2, plays a vital role in modulating T-cell activation and promoting immune responses. By binding to CD86, this antibody enables detection and analysis of this important protein in different cell types, offering insights into immune activation mechanisms.

Its compatibility with flow cytometry and other techniques makes it versatile for use in immunology research, particularly in studies related to autoimmunity, transplantation, and infectious diseases.With its ability to specifically target CD86, this antibody is a valuable tool for investigating the role of co-stimulatory molecules in immune regulation and disease pathogenesis. Researchers can utilize this antibody to delve deeper into the complex interplay between immune cells and develop potential therapies targeting CD86 for various immune-related conditions.

Product Name:CD86 Antibody, FITC
Product Sku:CPAB0369
Size:500μg
Host Species:Rat
Immunogen:Purified mouse LPS-activated B cells.
Clone:mB7-2.
Reactivity:Mouse
Applications:
Purification Method: Protein A
Isotype:IgG2a
Background:CD86 type I membrane protein is a member of the immunoglobulin superfamily which is expressed by antigen-presenting cells, and acts as the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. CD86 binding with CD28 protein is a co-stimulatory signal for initiation of the T-cell. CD86 binding with CTLA-4 negatively regulates T-cell activation and diminishes the immune response.
Synonyms:B70, B7-2, LAB72, CD28LG2, FUN-1, BU63.
Storage Buffer:Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

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