CD86 Monoclonal Antibody, Biotin [mB7-2] (CPAB0368)
- SKU:
- CPAB0368
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rat
- Isotype:
- IgG2a
- Clone:
- mB7-2
Frequently bought together:
Description
system_update_alt Datasheet
Product Name: | CD86 Antibody, Biotin |
Product Sku: | CPAB0368 |
Size: | 500μg |
Host Species: | Rat |
Immunogen: | Purified mouse LPS-activated B cells. |
Clone: | mB7-2. |
Reactivity: | Mouse |
Applications: |
Purification Method: | Protein A |
Isotype: | IgG2a |
Background: | CD86 type I membrane protein is a member of the immunoglobulin superfamily which is expressed by antigen-presenting cells, and acts as the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. CD86 binding with CD28 protein is a co-stimulatory signal for initiation of the T-cell. CD86 binding with CTLA-4 negatively regulates T-cell activation and diminishes the immune response. |
Synonyms: | B70, B7-2, LAB72, CD28LG2, FUN-1, BU63. |
Storage Buffer: | Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |