The CD83 Monoclonal Antibody (MAB80089) is specifically designed for research involving CD83, a cell surface protein known for its role in immune regulation and activation. This antibody, produced through hybridoma technology, is highly specific and reactive with human CD83 samples, making it ideal for use in various immunological studies.CD83 is a key regulator of immune responses, playing a crucial role in activating T cells and promoting immune tolerance. Its involvement in immune regulation makes it a valuable target for research into autoimmune diseases, allergies, and transplants. By targeting CD83, researchers can explore new avenues for therapeutic interventions aimed at modulating immune responses and treating inflammatory conditions.
This monoclonal antibody binds specifically to CD83, allowing for the detection and analysis of CD83 expression in various cell types and tissues. Its high specificity and sensitivity in applications such as flow cytometry, immunohistochemistry, and ELISA make it a valuable tool for studying the function and expression of CD83 in different physiological and pathological contexts. Unlocking the potential of CD83 through research can lead to the development of novel therapies and treatments for a range of immunological disorders.
Product Name:
CD83 Monoclonal Antibody
SKU:
CAB22379
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-143 of human CD83 (NP_004224.1).
The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9308
Clone Number:
ARC53759
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CD83 Rabbit mAb (CAB22379) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
