Cd82 Antibody (PACO25636)
- SKU:
- PACO25636
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Cd82 Antibody (PACO25636)
The CD82 Monoclonal Antibody (PACO25636) is a powerful tool for scientists conducting research on CD82, a cell surface protein associated with cell adhesion and migration. This antibody, developed using innovative technology, specifically targets the CD82 protein in human samples and is suitable for use in a variety of experimental techniques, including Western blotting.CD82, also known as KAI1, is known to play a crucial role in cell signaling and metastasis, making it a key focus in studies on cancer progression and treatment. By using the CD82 Monoclonal Antibody, researchers can gain valuable insights into the mechanisms by which CD82 influences tumor growth and metastatic spread.
Furthermore, the ability of this antibody to selectively bind to CD82 opens up new possibilities for investigating the potential therapeutic applications of targeting this protein in cancer therapy. By understanding the complex functions of CD82, researchers can develop targeted interventions that may inhibit tumor cell migration and invasion, ultimately leading to novel approaches for combating cancer.
| Antibody Name: | Cd82 Antibody (PACO25636) |
| Antibody SKU: | PACO25636 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Mouse, Human |
| Immunogen: | Recombinant Mouse CD82 antigen protein (111-227AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Cd82 antibody at 2µg/ml Lane 1: Jurkat whole cell lysate Lane 2: A549 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 30 kDa Observed band size: 30 kDa . |
| Background: | Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway. |
| Synonyms: | CD82 antigen (C33 antigen) (IA4) (Inducible membrane protein R2) (Metastasis suppressor Kangai-1 homolog) (CD antigen CD82), Cd82, Kai1 |
| UniProt Protein Function: | CD82: a widespread transmembrane protein of the tetraspanin family. A metastasis-suppressor whose decreased expression may be involved in malignant progression. Suppresses tumor metastasis of many cancers including cancers of the prostate, bladder, colon, cervix, liver, and lung (NSCLC). It is a target of estrogen receptor-mediated gene repression and is downregulated in primary human breast cancer. May be a prognostic marker for lung cancer and tumor metastatic potential. Interacts with cell surface proteins including integrins, cadherins, CD4, CD8, IGSF8. Modulates EGFR signaling. May suppress invasion by inhibiting integrin-dependent crosstalk with c-Met receptor and Src kinases. Its regulation of c-Met signaling apparently affects cancer cell migration.Protein type: Membrane protein, integral; Membrane protein, multi-pass; Cell surfaceCellular Component: integral to membrane; integral to plasma membrane; membraneBiological Process: cell surface receptor linked signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P40237 |
| NCBI GenInfo Identifier: | 209862915 |
| NCBI Gene ID: | 12521 |
| NCBI Accession: | NP_001129527.1 |
| UniProt Secondary Accession: | P40237 |
| UniProt Related Accession: | P40237 |
| Molecular Weight: | 29.5 kDa |
| NCBI Full Name: | CD82 antigen |
| NCBI Synonym Full Names: | CD82 antigen |
| NCBI Official Symbol: | Cd82Â Â |
| NCBI Official Synonym Symbols: | C33; IA4; Kai1; Tspan27; AA682076; AL023070Â Â |
| NCBI Protein Information: | CD82 antigen |
| UniProt Protein Name: | CD82 antigen |
| UniProt Synonym Protein Names: | C33 antigen; IA4; Inducible membrane protein R2; Metastasis suppressor Kangai-1 homolog; CD_antigen: CD82 |
| Protein Family: | CD82 antigen |
| UniProt Gene Name: | Cd82Â Â |
| UniProt Entry Name: | CD82_MOUSE |
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