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CD81 Rabbit Polyclonal Antibody (CAB5270)

SKU:
CAB5270
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology
  • Immunology Antibodies 2 Anti-CD81 Antibody CAB5270
  • Immunology Antibodies 2 Anti-CD81 Antibody CAB5270
  • Immunology Antibodies 2 Anti-CD81 Antibody CAB5270
$167 - $503
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:CD81 Rabbit Polyclonal Antibody
SKU:CAB5270
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 114-199 of human CD81 (NP_004347.1).
Sequence:VNKD QIAK DVKQ FYDQ ALQQ AVVD DDAN NAKA VVKT FHET LDCC GSST LTAL TTSV LKNN LCPS GSNI ISNL FKED CHQK IDDL FS
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:S5.7; CVID6; TAPA1; TSPAN28; CD81
Positive Sample:Raji,Mouse brain
Conjugate:Unconjugated
Cellular Localization:Membrane, Multi-pass membrane protein.
Calculated MW:26kDa
Observed MW:22kDa

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:975
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of Rat brain, using CD81 antibody (CAB5270) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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