The CD81 Antigen Polyclonal Antibody (CAB5270) is a vital tool for researchers studying the CD81 antigen, a cell surface protein involved in various cellular processes, including cell adhesion, migration, and immune response coordination. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been rigorously tested for use in Western blot applications.By specifically binding to the CD81 antigen, this antibody enables accurate detection and analysis of CD81 protein expression in a wide range of cell types.
This makes it an ideal choice for investigations in immunology, oncology, and cell biology.The CD81 antigen plays a crucial role in immune regulation and is implicated in diseases such as cancer and viral infections. Understanding its function and expression patterns is essential for developing targeted therapies and diagnostic tools. The CD81 Antigen Polyclonal Antibody (CAB5270) provides researchers with a reliable tool to advance their studies and contribute to the field of biomedical research.
Product Name:
CD81 Rabbit Polyclonal Antibody
SKU:
CAB5270
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 114-199 of human CD81 (NP_004347.1).
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
975
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of Rat brain, using CD81 antibody (CAB5270) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
