The CD80 Polyclonal Antibody (CAB16039) is a powerful tool for researchers studying CD80, a key co-stimulatory molecule involved in immune responses. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the CD80 protein, this antibody enables precise detection and analysis in various cell types, making it ideal for investigations in immunology and cancer research.CD80, also known as B7-1, is a critical component of the immune system, providing essential signals for T cell activation and function. Its role in regulating immune responses makes it a valuable target for research into autoimmune diseases, transplantation, and infectious diseases.
Understanding the function of CD80 is essential for developing new strategies to modulate immune responses and potentially treat a variety of immune-related disorders.Overall, the CD80 Polyclonal Antibody is a reliable tool for researchers looking to delve deeper into the functions and mechanisms of CD80 in immunology and beyond. Its specificity and sensitivity make it a valuable asset for advancing our understanding of immune regulation and potential therapeutic interventions.
Product Name:
CD80 Rabbit Polyclonal Antibody
SKU:
CAB16039
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CD80 (NP_005182.1).
The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.
Purification Method:
Affinity purification
Gene ID:
941
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat lung, using CD80 Rabbit pAb (CAB16039) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
