CD80 Monoclonal Antibody [mB7-1] (CPAB0352)
- SKU:
- CPAB0352
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rat
- Isotype:
- IgG2a
- Clone:
- mB7-1
Description
CD80 Monoclonal Antibody [mB7-1] (CPAB0352)
The CD80 Monoclonal Antibody (CPAB0352) is a potent tool for research involving CD80, a crucial co-stimulatory molecule involved in T cell activation and immune responses. This antibody, generated in mice, exhibits high specificity for human CD80 and is validated for use in applications such as flow cytometry and immunohistochemistry.CD80, also known as B7-1, plays a vital role in regulating the immune response by providing the necessary signals for T cell activation and proliferation. Its expression on antigen-presenting cells is essential for initiating effective immune responses against pathogens and cancer cells.
The CD80 Monoclonal Antibody binds specifically to CD80, allowing for precise detection and analysis of this protein in various cell types and tissues.Researchers studying immune regulation, autoimmune diseases, and cancer biology will find the CD80 Monoclonal Antibody to be a valuable tool in their investigations. By understanding the role of CD80 in immune activation and tolerance, novel therapeutic strategies targeting this molecule can be developed to modulate immune responses in various disease settings.
| Product Name: | CD80 Antibody |
| Product Sku: | CPAB0352 |
| Size: | 500μg |
| Host Species: | Rat |
| Immunogen: | Purified mouse LPS-activated B cells. |
| Clone: | mB7-1. |
| Reactivity: | Mouse |
| Applications: |
| Purification Method: | Ion exchange column. |
| Isotype: | IgG2a |
| Background: | The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells CD-80 is involved in the costimulatory signal essential for t- lymphocyte activation. t-cell proliferation and cytokine production is induced by the binding of cd28 or ctla-4 to this receptor. |
| Synonyms: | LAB7, CD28LG, CD28LG1, CD28LG1, B71. |
| Storage Buffer: | Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |
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