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CD8 Monoclonal Antibody, Biotin [hCD8] (CPAB0300)

SKU:
CPAB0300
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
hCD8
$792
Frequently bought together:

Description

system_update_alt Datasheet

CD8 Monoclonal Antibody, Biotin [hCD8] (CPAB0300)

The CD8 Antibody (Biotin) (CPAB0300) is a high-quality research tool designed to specifically detect and analyze CD8, a critical cell surface marker involved in immune responses. This polyclonal antibody, generated in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blotting.CD8, also known as the T-cell co-receptor, plays a crucial role in immune function by identifying foreign antigens and initiating immune responses. The CD8 Antibody (Biotin) binds to the CD8 protein, allowing for the detection and analysis of this marker in different cell types.

This makes it an ideal tool for studies in immunology, oncology, and infectious diseases.Understanding the expression and activity of CD8 is essential for unraveling its role in immune regulation and disease pathology. The CD8 Antibody (Biotin) provides researchers with a reliable tool to investigate the function of CD8 in various biological processes and disease states, ultimately leading to the development of new therapies and treatments.

Product Name:CD8 Antibody, Biotin
Product Sku:CPAB0300
Size:500μg
Host Species:Mouse
Immunogen:Purified human PBL CD8+ T cells.
Clone:hCD8.
Reactivity:Human
Applications:
Purification Method:Ion exchange column.
Isotype:IgG2a
Background:CD8 is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 acts as a co-receptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional CD8 is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 identifies cytotoxic/suppressor t-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of t-cell mediated killing. CD8 alpha chains binds to class-I MHC molecules alpha-3 domains.
Synonyms:CD8, MAL, p32.
Storage Buffer:Lyophilized: store at 4C. After reconstitution, if not intended for use within a month, aliquot and store at -20C.

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