The CD79b Polyclonal Antibody (CAB2033) is a valuable tool for research involving CD79b, a key component of the B cell receptor complex. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been rigorously validated for use in Western blot applications. By specifically targeting the CD79b protein, researchers can effectively analyze and detect its expression in various cell types, making it an ideal choice for studies in immunology and cancer research.CD79b is an essential protein involved in B cell signaling and activation, playing a critical role in the adaptive immune response.
Understanding the function and regulation of CD79b is crucial for investigating immune dysregulation in diseases such as leukemia, lymphoma, and autoimmune disorders. By targeting CD79b with this polyclonal antibody, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify novel therapeutic targets for treatment.
Product Name:
CD79B Rabbit Polyclonal Antibody
SKU:
CAB2033
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 130-229 of human CD79B (NP_000617.1).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
26kDa
Observed MW:
36kDa
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
974
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Raji cells, using CD79B Rabbit pAb (CAB2033) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
