The CD79A Polyclonal Antibody (CAB0331) is a vital tool for researchers studying CD79A, a key component of the B cell receptor complex essential for B cell development and function. This antibody, generated in rabbits, demonstrates high specificity and sensitivity to human samples, making it ideal for Western blot analysis. By binding to the CD79A protein, this antibody enables precise detection and analysis of CD79A expression in various cell types, providing important insights into B cell biology and immune responses.
CD79A is a crucial signaling molecule involved in B cell activation and antibody production, making it a valuable target for research in immunology and cancer biology. Dysregulation of CD79A has been implicated in various B cell malignancies, highlighting the importance of understanding its role in disease progression. By using the CD79A Polyclonal Antibody, researchers can uncover the mechanisms underlying B cell function and potential therapeutic strategies for B cell-related disorders.
Product Name:
CD79a Rabbit Polyclonal Antibody
SKU:
CAB0331
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 165-225 of human CD79a (NP_001774.1).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
25kDa
Observed MW:
40-50kDa
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
973
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Raji cells, using CD79a Rabbit pAb (CAB0331) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
