CD74 Rabbit Monoclonal Antibody (CAB9149)
- SKU:
- CAB9149
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | CD74 Rabbit Monoclonal Antibody |
SKU: | CAB9149 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CD74 (P04233). |
Sequence: | MHRR RSRS CRED QKPV MDDQ RDLI SNNE QLPM LGRR PGAP ESKC SRGA LYTG FSIL VTLL LAGQ ATTA YFLY QQQG RLDK LTVT SQNL QLEN LRMK LPKP |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | II; p33; CLIP; DHLAG; HLADG; Ia-GAMMA; CD74 |
Positive Sample: | HepG2,Raji |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Endoplasmic reticulum membrane, Endosome, Golgi apparatus, Lysosome, Single-pass type II membrane protein, trans-Golgi network. |
Calculated MW: | 34kDa |
Observed MW: | 30-40kDa |
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method: | Affinity purification |
Gene ID: | 972 |
Clone Number: | ARC1452 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |