CD74 Rabbit Polyclonal Antibody (CAB5667)
- SKU:
- CAB5667
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | CD74 Rabbit Polyclonal Antibody |
SKU: | CAB5667 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 73-232 of human CD74 (NP_004346.1). |
Sequence: | QQQG RLDK LTVT SQNL QLEN LRMK LPKP PKPV SKMR MATP LLMQ ALPM GALP QGPM QNAT KYGN MTED HVMH LLQN ADPL KVYP PLKG SFPE NLRH LKNT METI DWKV FESW MHHW LLFE MSRH SLEQ KPTD APPK ESLE LEDP SSGL GVTK QDLG PVPM |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | II; p33; CLIP; DHLAG; HLADG; Ia-GAMMA; CD74 |
Positive Sample: | Daudi |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Endoplasmic reticulum membrane, Endosome, Golgi apparatus, Lysosome, Single-pass type II membrane protein, trans-Golgi network. |
Calculated MW: | 34kDa |
Observed MW: | 30-40kDa |
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method: | Affinity purification |
Gene ID: | 972 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |