The CD69 Polyclonal Antibody (CAB2045) is a powerful tool for researchers studying the CD69 protein, a key regulator of immune responses. Produced in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the CD69 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an invaluable asset for studies in immunology and cancer research.CD69, also known as activation inducer molecule, plays a crucial role in modulating immune activation and initiating immune responses.
Its involvement in immune signaling pathways makes it a promising target for research into diseases such as cancer, autoimmune disorders, and inflammatory conditions. By unraveling the function of CD69, researchers can gain insights that may lead to the development of novel therapies aimed at manipulating immune responses in these disease contexts.
Product Name:
CD69 Rabbit Polyclonal Antibody
SKU:
CAB2045
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence within amino acids 1-80 of human CD69 (NP_001772.1).
Sequence:
MSSE NCFV AENS SLHP ESGQ ENDA TSPH FSTR HEGS FQVP VLCA VMNV VFIT ILII ALIA LSVG QYNC PGQY TFSM PSDS
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
AIM; EA1; MLR-3; CLEC2C; GP32/28; BL-AC/P26; CD69
Positive Sample:
U-937,Mouse lung,Mouse spleen,Rat lung,Rat spleen
Conjugate:
Unconjugated
Cellular Localization:
Membrane, Single-pass type II membrane protein.
Calculated MW:
23kDa
Observed MW:
25-45kDa
This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets.
Purification Method:
Affinity purification
Gene ID:
969
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CD69 antibody (CAB2045) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
