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CD62E Monoclonal Antibody [hCD62E] (CPAB0311)

SKU:
CPAB0311
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
hCD62E
$792
Frequently bought together:

Description

system_update_alt Datasheet
Product Name:CD62E Antibody
Product Sku:CPAB0311
Size:500μg
Host Species:Mouse
Immunogen:Purified, Activated T-Cells.
Clone:hCD62E.
Reactivity:Human
Applications:
Purification Method:Ion exchange column.
Isotype:IgG1
Background:E-Selectin belongs to a family of divalent cation-dependent carbohydrate-binding glycoproteins or adhesion molecules. CD62E is expressed on the surface of endothelial cells and mediates the interaction of leukocytes and platelets with endothelial cells during an inflammatory response. CD62E is found in cytokine-stimulated endothelial cells and is accountable for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It demonstrates structural features such as the existence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. E-Selectin participates in the interaction between leukocytes and the endothelium and appears to be involved in the pathogenesis of atherosclerosis.
Synonyms:E-selectin, Endothelial leukocyte adhesion molecule 1, ELAM-1, Leukocyte-endothelial cell adhesion molecule 2, LECAM2, CD62E antigen, SELE, ELAM1, ELAM, ESEL, CD62E.
Storage Buffer:Lyophilized: store at 4 C. After reconstitution, if not intended for use within a month, aliquot and store at -20 C.

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