The CD6 Polyclonal Antibody (CAB8107) is a valuable tool for researchers studying the CD6 protein, a cell surface molecule involved in immune responses. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the CD6 protein, this antibody enables precise detection and analysis in various cell types, making it ideal for investigations in immunology and cancer research.CD6, also known as T12 or TP120, is a crucial player in immune system regulation, acting as a co-stimulatory molecule that enhances T cell activation and proliferation.
Its role in modulating immune responses makes it a key focus in research related to autoimmune diseases, inflammation, and cancer. Understanding the function of CD6 is essential for developing therapies that target or modulate immune responses in these conditions. Overall, the CD6 Polyclonal Antibody (CAB8107) serves as a reliable tool for researchers seeking to explore the role of CD6 in immune regulation and its potential implications in various disease states.
Product Name:
CD6 Rabbit Polyclonal Antibody
SKU:
CAB8107
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 424-668 of human CD6 (NP_006716.3).
Cell membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
72kDa
Observed MW:
110kDa
This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
923
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CD6 antibody (CAB8107) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
