The CD58 Polyclonal Antibody (CAB5684) is a valuable tool for researchers studying CD58, a cell surface protein involved in immune responses and T-cell activation. This antibody, produced in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications. By specifically targeting the CD58 protein, this antibody enables precise detection and analysis in various cell types, making it an essential component for studies in immunology and cancer research.
CD58, also known as LFA-3, plays a crucial role in immune cell communication and regulation, particularly in T-cell adhesion and activation. Its involvement in immune responses makes it a key player in understanding diseases such as cancer, autoimmune disorders, and inflammation. The CD58 Polyclonal Antibody offers researchers the opportunity to delve deep into the mechanisms of CD58 function, leading to potential therapeutic advancements in immune-related conditions.
Product Name:
CD58 Rabbit Polyclonal Antibody
SKU:
CAB5684
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 40-220 of human CD58 (NP_001770.1).
Cell membrane, GPI-anchor, Lipid-anchor, Single-pass type I membrane protein.
Calculated MW:
28kDa
Observed MW:
70kDa
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
965
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CD58 Antibody (CAB5684) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
