The CD58 Monoclonal Antibody is a highly specific tool for research involving the CD58 protein, also known as LFA-3. This cell surface glycoprotein is involved in T-cell co-stimulation and adhesion, crucial for immune responses. The antibody, generated in mice, is ideal for use in various research applications, including flow cytometry and immunohistochemistry.CD58 plays a vital role in immune cell interactions, facilitating the activation and regulation of T-cells. Its involvement in immune responses makes it a key target for studies in immunology, infectious diseases, and autoimmune disorders.
The CD58 Monoclonal Antibody specifically binds to the CD58 protein, allowing for accurate detection and analysis in different cell types and tissues.Understanding the function and regulation of CD58 is essential for advancing knowledge in immune system modulation and therapeutics. This antibody offers researchers a reliable tool for investigating the role of CD58 in various physiological and pathological processes, aiding in the development of novel strategies for treating immune-related disorders.
Product Name:
CD58 Monoclonal Antibody
SKU:
CAB22276
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 29-215 of human CD58 (NP_001770.1).
Cell membrane, GPI-anchor, Lipid-anchor, Single-pass type I membrane protein.
Calculated MW:
28kDa
Observed MW:
55-70kDa
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
965
Clone Number:
ARC54834
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CD58 antibody (CAB22276) at1:20000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
