The CD55 Polyclonal Antibody (CAB13918) is a valuable tool for researchers studying CD55, a key protein involved in immune regulation and complement system control. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to CD55, this antibody allows for the detection and analysis of the protein in various cell types, making it an essential tool for studies in immunology and related fields.CD55, also known as decay-accelerating factor (DAF), is a critical regulator of the complement system, playing a vital role in protecting cells from complement-mediated damage.
Dysregulation of CD55 has been implicated in various diseases, including autoimmune disorders and inflammatory conditions. Therefore, researching the function and expression of CD55 is essential for understanding its role in health and disease.Overall, the CD55 Polyclonal Antibody (CAB13918) offers researchers a reliable and specific tool for investigating the function of CD55 in immune regulation and complement system control. Its applications in Western blotting make it a versatile resource for studies aimed at unraveling the complexities of immune response modulation in various physiological and pathological conditions.
Product Name:
CD55 Rabbit Polyclonal Antibody
SKU:
CAB13918
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human CD55 (NP_000565.1).
Cell membrane, GPI-anchor, Lipid-anchor, Secreted, Single-pass type I membrane protein.
Calculated MW:
41kDa
Observed MW:
51kDa
This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins.
Purification Method:
Affinity purification
Gene ID:
1604
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of A-549 cells, using CD55 antibody (CAB13918) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
