The CD55 Polyclonal Antibody (CAB1228) is a crucial tool for researchers studying CD55, a cell surface protein involved in immune regulation and protection against complement-mediated damage. This antibody, generated in rabbits, is highly specific and reactive to human samples, making it an ideal choice for Western blot applications.CD55, also known as decay-accelerating factor (DAF), plays a vital role in protecting cells from complement activation, thereby preventing unnecessary immune responses and tissue damage. Dysregulation of CD55 has been linked to various diseases, including autoimmune disorders and inflammatory conditions.
Understanding the function of CD55 is essential for developing targeted therapies and interventions to treat these diseases.By utilizing the CD55 Polyclonal Antibody, researchers can effectively detect and analyze CD55 protein levels in various cell types, providing valuable insights into its role in immune regulation and disease pathogenesis. This antibody is a valuable tool for studies in immunology, cancer research, and other fields where CD55 is of interest.
Product Name:
CD55 Rabbit Polyclonal Antibody1
SKU:
CAB1228
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human CD55 (NP_000565.1).
Cell membrane, GPI-anchor, Lipid-anchor, Secreted, Single-pass type I membrane protein.
Calculated MW:
41kDa
Observed MW:
60-70kDa
This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins.
Purification Method:
Affinity purification
Gene ID:
1604
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CD55 Rabbit pAb (CAB1228) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
