The CD55 Rabbit Monoclonal Antibody is a crucial tool for researchers studying CD55, a cell surface protein known for its role in regulating the complement system and protecting cells from complement-mediated damage. This antibody, generated in rabbits, exhibits high specificity and sensitivity for CD55 in human samples, making it an excellent choice for applications such as Western blotting and immunohistochemistry.CD55, also called decay accelerating factor (DAF), is involved in preventing the formation of the membrane attack complex (MAC) and promoting the decay of C3 and C5 convertases, ultimately guarding cells against complement-mediated lysis.
Dysregulation of CD55 expression has been linked to various diseases, including autoimmune disorders, hemolytic anemia, and cancer. By utilizing the CD55 Rabbit Monoclonal Antibody, researchers can gain valuable insights into the function and expression of CD55 in different cell types and tissues, paving the way for advancements in immunology and disease research.
Product Name:
CD55 Rabbit Monoclonal Antibody
SKU:
CAB11283
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CD55 (P08174).
Cell membrane, GPI-anchor, Lipid-anchor, Secreted, Single-pass type I membrane protein.
Calculated MW:
41kDa
Observed MW:
78kDa
This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins.
Purification Method:
Affinity purification
Gene ID:
1604
Clone Number:
ARC0568
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using CD55 Rabbit mAb (CAB11283) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
