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CD52 monoclonal antibody (FITC) (AGIM0323)

SKU:
AGIM0323
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
HI186
Conjugation:
FITC
Applications:
FC
$215
Frequently bought together:

Description

system_update_altDatasheet
Product Name:CD52 monoclonal antibody (FITC)
Product Code:AGIM0323
Size:100 µL
Reactivity:Human
Clone:HI186
Applications:Flow Cytometry
Conjugate:FITC
Isotype:IgG2b
Host Species:Mouse
Storage:Store at 4°C. Avoid prolonged exposure to light.
Uniprot:P31358 
Background:CD52 (CAMPATH-1, HE5) is a highly glycosylated GPI-anchored 21-28 kDa glycopeptide which is present at high levels on lymphocytes, macrophages, epithelial cells of male reproductive tract and mature sperm. Its 12-amino acid beckbone carries a complex N-linked carbohydrate moiety, which differs between sperm and leukocyte CD52, as well as the GPI anchor does. CD52 can be acquired by sperm cells from seminal plasma, where it is released by epithelial cells. Although CD52 is not an essential T-cell costimulator, its triggering results in activation of normal human T cells. CD52 is a very good target for antibody/complementmediated cell lysis.

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