The CD5 Polyclonal Antibody (CAB6882) is a valuable tool for researchers studying the CD5 cell surface molecule, which is known for its role in immune regulation. This antibody, produced in rabbits, is highly specific for human samples and is suitable for use in Western blotting applications. By targeting the CD5 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it a versatile option for studies in immunology and cancer research.CD5 is a key player in immune function, acting as a modulator of immune responses and potentially influencing the development of various diseases.
Research into CD5's function can provide insights into conditions such as cancer, autoimmune disorders, and chronic inflammation. By understanding the mechanisms by which CD5 operates, researchers can work towards developing targeted therapies that either enhance or suppress immune responses, paving the way for new treatment options in these areas.
Product Name:
CD5 Rabbit Polyclonal Antibody
SKU:
CAB6882
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 158-371 of human CD5 (NP_055022.2).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
55kDa
Observed MW:
65kDa
This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
921
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using CD5 Rabbit pAb (CAB6882) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
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