The APC Anti-Human CD48 Antibody (156-4H9) showcased on www.assaygenie.com is a potent tool for research and analysis of CD48, a key cell surface protein involved in immune response modulation. This antibody, targeted against human samples and meticulously validated for various applications, offers researchers a reliable means to detect and study CD48 in different cell types.CD48, a significant molecule in immune regulation, plays a pivotal role in immune responses by interacting with various immune cells and influencing their functions. Its involvement in immune signaling pathways makes it a prime target for investigations related to immune system behavior, autoimmune diseases, and inflammatory conditions.
By delving into the mechanisms of CD48 action, researchers can gain insights that could lead to the development of novel therapeutic strategies for diseases like cancer and autoimmune disorders.The APC Anti-Human CD48 Antibody (156-4H9) is a valuable asset for immunology and cancer research, providing a direct route to studying the functions and interactions of CD48 in biological systems. Its specificity and efficacy make it an indispensable tool for unraveling the complexities of immune regulation and its implications in various health conditions.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P09326
Gene ID:
962
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD48 is a 40-47 kD GPI-anchored membrane protein, also known as Blast-1 and HuLy-m3. It is a member of the CD2 family that contains 2 IgSF domains and is widely expressed on both resting and activated hematopoietic cells with the exception of granulocytes, platelets, and erythrocytes. CD48 binds to CD2 at a considerably (>100-fold) lower affinity than CD58. It is thought to contribute to T cell activation. The cytoplasmic tail of CD48 has been shown to bind to the kinases Lck and Fyn.