CD45 Monoclonal Antibody, Biotin [hCD45] (CPAB0322)
- SKU:
- CPAB0322
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- hCD45
Description
CD45 Monoclonal Antibody, Biotin [hCD45] (CPAB0322)
The CD45 Antibody (Biotin) (CPAB0322) is a crucial tool for researchers studying CD45, a key cell surface protein involved in immune cell function. This polyclonal antibody, produced in rabbits, is highly specific for human samples and is optimized for Western blot applications. By binding to the CD45 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential tool for immunology research and studies on immune cell signaling pathways.CD45, also known as leukocyte common antigen, is a critical regulator of immune cell activation and signaling.
Its role in immune response modulation makes it a valuable target for research into autoimmune diseases, infectious diseases, and cancer. Understanding the function of CD45 is essential for developing targeted therapies that manipulate immune cell activity in various disease contexts.Overall, the CD45 Antibody (Biotin) (CPAB0322) is a reliable and specific tool for researchers studying immune cell function and signaling pathways involving CD45. Its high reactivity and specificity for human samples make it an indispensable asset for advancing research in immunology and related fields.
Product Name: | CD45 Antibody, Biotin |
Product Sku: | CPAB0322 |
Size: | 500μg |
Host Species: | Mouse |
Immunogen: | Purified human T-Cells. |
Clone: | hCD45. |
Reactivity: | Human |
Applications: |
Purification Method: | Protein A |
Isotype: | IgG2a |
Background: | CD45 leukocyte common antigen (LCA) belongs to the family of at least four isoforms of membrane glycoproteins (220, 205, 190, 180kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant non-hematopoietic tissues. The intracellular portion of these molecules has protein phosphatase activity and is involved in regulation of transmembrane signals. |
Synonyms: | Leukocyte common antigen, EC 3.1.3.48, L-CA, T200, CD45 antigen, PTPRC, LCA, LY5, B220, CD45, GP180. |
Storage Buffer: | Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |