The CD44 Rabbit Polyclonal Antibody (CAB16806) is a valuable tool for researchers studying CD44, a cell surface glycoprotein involved in cell adhesion, migration, and signaling processes. The antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the CD44 protein, this antibody enables the detection and analysis of CD44 expression in a wide range of cell types.CD44 is a versatile molecule known for its involvement in processes such as cell adhesion, lymphocyte activation, and lymph node homing. Its diverse functions have made it a focus of research in various fields, including immunology, cancer biology, and stem cell research.
Understanding the role of CD44 in these processes is crucial for developing targeted therapies and diagnostic tools for diseases such as cancer, inflammation, and metastasis.Overall, the CD44 Rabbit Polyclonal Antibody (CAB16806) is a reliable tool for researchers seeking to explore the role of CD44 in cellular processes and disease pathways. Its high specificity and sensitivity make it an essential component of any study involving CD44 protein expression and function.
Product Name:
CD44 Rabbit Polyclonal Antibody
SKU:
CAB16806
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 148-247 of human CD44 (NP_000601.3).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
82kDa
Observed MW:
Refer to figures
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
Purification Method:
Affinity purification
Gene ID:
960
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of C6 cells using CD44 antibody (CAB16806) at dilution of 1:100. Blue: DAPI for nuclear staining.
