Description
CD44 Mouse Monoclonal Antibody [mCD44] (CPAB0372)
The CD44 Mouse Monoclonal Antibody (CPAB0372) is a valuable tool for researchers studying CD44, a cell surface glycoprotein involved in cell adhesion and migration. This antibody, generated in mice, demonstrates high specificity and reactivity with mouse samples, making it an excellent choice for Western blot, immunofluorescence, and flow cytometry applications.CD44 is known to play a crucial role in cancer progression, stem cell migration, and immune cell activation. By targeting CD44 with this monoclonal antibody, researchers can investigate its function in various cellular processes and disease states.
Understanding the role of CD44 in cancer and immune response modulation may lead to the development of novel therapeutic strategies for treating cancer and inflammatory conditions.Overall, the CD44 Mouse Monoclonal Antibody (CPAB0372) is a versatile tool for researchers interested in studying the functions of CD44 in different biological systems, providing valuable insights into its potential as a therapeutic target in cancer and immunology research.
Product Name: | CD44 Mouse Antibody |
Product Sku: | CPAB0372 |
Size: | 500μg |
Host Species: | Rat |
Immunogen: | CD44 enriched mouse LN T cells. |
Clone: | mCD44. |
Reactivity: | Mouse |
Applications: | Immunohistochemistry |
Purification Method: | Protein A |
Isotype: | IgG |
Background: | CD44 is a cell-surface glycoprotein that plays a role in cell-cell interactions, cell adhesion and migration. CD44 is a receptor for hyaluronic acid and also interacts with other ligands, such as osteopontin, collagens, and matrix metalloproteinases. CD44 participates in a wide variety of cellular functions such as lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. CD44 and CD49d are putative activity markers and CD44 a potential novel therapeutic target in multiple sclerosis. Increased CD44 antigen is associated with relapses in non-small cell lung cancers. |
Synonyms: | MDU2, MDU3, MIC4, CDW44, CSPG8, HCELL, HUTCH-I, Phagocytic glycoprotein I, PGP-1, Extracellular matrix receptor-III, ECMR-III, Hermes antigen, Hyaluronate receptor, Heparan sulfate proteoglycan, Epican) CDw44. |
Storage Buffer: | Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |