CD44 Anti Human [P5C10AT] (CPAB0339)
- SKU:
- CPAB0339
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
CD44 Anti Human [P5C10AT] (CPAB0339)
The CD44 Monoclonal Antibody (CPAB0339) is a valuable tool for researchers studying CD44, a cell surface glycoprotein involved in cell adhesion and migration. This antibody, produced in mice, shows high specificity and sensitivity in detecting CD44 protein in human samples, making it suitable for Western blot and immunohistochemistry applications.CD44 is known for its role in various cellular processes, such as cell-cell interactions, cell signaling, and cell migration. Its overexpression has been linked to cancer progression and metastasis, making it a potential target for cancer therapy and prognosis.
By targeting CD44 with this antibody, researchers can gain insights into its function in different cell types and tissues, aiding in the study of cancer biology and potential therapeutic interventions.With its ability to specifically detect CD44 protein in human samples, the CD44 Monoclonal Antibody (CPAB0339) is a valuable tool for immunology and cancer research, offering researchers a reliable means of studying the role of CD44 in various biological processes and disease states.
Product Name: | CD44 Anti Human |
Product Sku: | CPAB0339 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human CD44 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CD44 amino acids 21-145 purified from Ecoli. |
Clone: | P5C10AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | CD44 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG2b |
Background: | CD44 is a cell-surface glycoprotein that plays a role in cell-cell interactions, cell adhesion and migration. CD44 is a receptor for hyaluronic acid and also interacts with other ligands, such as osteopontin, collagens, and matrix metalloproteinases. CD44 participates in a wide variety of cellular functions such as lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. CD44 and CD49d are putative activity markers and CD44 a potential novel therapeutic target in multiple sclerosis. Increased CD44 antigen is associated with relapses in non-small cell lung cancers. |
Synonyms: | MDU2, MDU3, MIC4, CDW44, CSPG8, HCELL, HUTCH-I, Phagocytic glycoprotein I, PGP-1, Extracellular matrix receptor-III, ECMR-III, Hermes antigen, Hyaluronate receptor, Heparan sulfate proteoglycan, Epican, CDw44. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |