CD41/ITGA2B Rabbit Monoclonal Antibody (CAB11490)
- SKU:
- CAB11490
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CD41/ITGA2B Rabbit Monoclonal Antibody |
SKU: | CAB11490 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CD41/ITGA2B (P08514). |
Sequence: | MARA LCPL QALW LLEW VLLL LGPC AAPP AWAL NLDP VQLT FYAG PNGS QFGF SLDF HKDS HGRV AIVV GAPR TLGP SQEE TGGV FLCP WRAE GGQC PSLL |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | GT; GT1; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16; PPP1R93; CD41/ITGA2B |
Positive Sample: | A549,PC-3,K-562,Mouse spleen,Rat brain,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 113kDa |
Observed MW: | 137kDa |
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia.
Purification Method: | Affinity purification |
Gene ID: | 3674 |
Clone Number: | ARC0620 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |