The CD40LG Polyclonal Antibody (CAB13002) is a valuable tool for researchers studying CD40LG, a crucial protein involved in immune responses and inflammation. This antibody, produced in rabbits, offers high reactivity with human samples and is specifically validated for Western blot applications. By binding to CD40LG, researchers can accurately detect and analyze this protein in various cell types, making it ideal for studies in immunology, cancer research, and other related fields.CD40LG, also known as CD154, plays a vital role in activating immune cells and regulating immune responses.
It is an essential mediator in the communication between T cells and antigen-presenting cells, contributing to the initiation and regulation of immune reactions. Understanding the function of CD40LG is key to exploring its potential role in diseases such as cancer, autoimmune disorders, and inflammatory conditions. This antibody provides researchers with a valuable tool to investigate the intricate mechanisms involving CD40LG and its impact on immune system regulation and disease development.
Product Name:
CD40L Rabbit Polyclonal Antibody
SKU:
CAB13002
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CD40L (NP_000065.1).
Cell membrane, Secreted, Single-pass type II membrane protein.
Calculated MW:
29kDa
Observed MW:
25-30kDa
The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
Purification Method:
Affinity purification
Gene ID:
959
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CD40L Rabbit pAb (CAB13002) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
