The CD40L Rabbit Monoclonal Antibody (CAB19019) is a key tool for researchers studying CD40L, a cell surface protein involved in immune responses and inflammation. This antibody, derived from rabbits, is highly specific and reliable for use in various applications such as Western blotting and immunohistochemistry.CD40L, also known as CD154, is primarily expressed on activated T cells and is a crucial player in the regulation of immune responses. By targeting the CD40L protein, this antibody enables researchers to detect and analyze its expression in different cell types, making it a valuable asset in immunology and cancer research.
Furthermore, understanding the role of CD40L in immune regulation is essential for developing new therapies for diseases such as cancer, autoimmune disorders, and inflammatory conditions. With its high reactivity and specificity, the CD40L Rabbit Monoclonal Antibody (CAB19019) provides researchers with a powerful tool to further their understanding of CD40L's functions and its potential as a therapeutic target.
Product Name:
CD40L Rabbit Monoclonal Antibody
SKU:
CAB19019
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CD40L (P29965).
Cell membrane, Secreted, Single-pass type II membrane protein.
Calculated MW:
29kDa
Observed MW:
36kDa
The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
Purification Method:
Affinity purification
Gene ID:
959
Clone Number:
ARC0399
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CD40L antibody (CAB19019) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
