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CD40 Monoclonal Antibody [hCD40] (CPAB0324)

SKU:
CPAB0324
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
hCD40
€660
Frequently bought together:

Description

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CD40 Monoclonal Antibody [hCD40] (CPAB0324)

The CD40 Polyclonal Antibody (CPAB0324) is a valuable tool for researchers studying CD40, a cell surface receptor involved in immune responses and cell signaling. This antibody, raised in rabbits, has high reactivity with human samples and is validated for use in various applications, including Western blotting. It specifically targets the CD40 protein, enabling accurate detection and analysis in different cell types.CD40 is a critical player in the immune system, regulating B cell activation and antibody production. Its role in immune responses and inflammation makes it a key target for research in immunology, cancer, and autoimmune diseases.

Understanding the function of CD40 can provide insights into potential treatments for conditions where immune dysregulation plays a role.Overall, the CD40 Polyclonal Antibody (CPAB0324) is a valuable tool for researchers looking to explore the role of CD40 in various physiological and pathological processes. Its specificity and reliability make it a versatile option for studies aiming to dissect the intricate mechanisms of immune regulation and cell signaling.

Product Name:CD40 Antibody
Product Sku:CPAB0324
Size:500μg
Host Species:Mouse
Immunogen:Activated Human B cells.
Clone:hCD40.
Reactivity:Human
Applications:
Purification Method: Protein A
Isotype:IgG1
Background:CD40 is part of the TNF-receptor superfamily. CD40 is a necessary mediator for vast range of immune and inflammatory responses together with T cell-dependent immunoglobulin class switching, memory B cell growth, and germinal center formation. The transcription factor AKNA regulates the expression of CD40 and its ligand, which is vital for homotypic cell interactions. Adaptor protein TNFR2 interacts with CD40 and serves as a mediator of the signal transduction. The interaction of CD40 and its ligand is crucial for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is the receptor for TNFSF5/CD40L.
Synonyms:p50, Bp50, CDW40, MGC9013, TNFRSF5, CD40.
Storage Buffer:Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

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