The Human CD4 Monoclonal Antibody (RPA-T4, AGEL0397) offered by AssayGenie is a cutting-edge tool for researchers investigating the CD4 protein, a key player in the immune system. This monoclonal antibody is specifically designed for use with human samples, providing high sensitivity and specificity in a range of applications.CD4 is a vital co-receptor involved in the recognition of antigens by T cells, orchestrating immune responses against pathogens and diseased cells. The RPA-T4 antibody binds specifically to the CD4 protein, enabling precise detection and analysis in various cell types.
This makes it an indispensable resource for studies in immunology, infectious diseases, autoimmune disorders, and HIV/AIDS research.With its superior performance and reliability, the Human CD4 Monoclonal Antibody (RPA-T4, AGEL0397) from AssayGenie empowers researchers to unravel the intricate mechanisms of immune responses and develop innovative therapeutic strategies. Unlock the potential of your research with this advanced antibody and delve deeper into the complexities of the immune system.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7).