The CD3G Polyclonal Antibody (CAB1938) is a valuable tool for researchers studying CD3G, a key component of the T-cell receptor complex involved in immune response. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the CD3G protein, this antibody enables accurate detection and analysis of CD3G in various cell types, making it an essential asset for studies in immunology and cancer research.
CD3G plays a crucial role in T-cell signaling and activation, making it a significant target for understanding immune responses and developing therapies for diseases such as cancer, autoimmune disorders, and infectious diseases. By studying the function and regulation of CD3G, researchers can gain insights into T-cell activation mechanisms and potential therapeutic targets for manipulating immune responses in various pathological conditions.
Product Name:
CD3G Polyclonal Antibody
SKU:
CAB1938
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 23-116 of human CD3G (NP_000064.1).
The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.
Purification Method:
Affinity purification
Gene ID:
917
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CD3G antibody (CAB1938) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 45s.
