CD3E Rabbit Polyclonal Antibody (CAB1753)
- SKU:
- CAB1753
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | CD3E Rabbit Polyclonal Antibody |
SKU: | CAB1753 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-126 of human CD3E (NP_000724.1). |
Sequence: | MQSG THWR VLGL CLLS VGVW GQDG NEEM GGIT QTPY KVSI SGTT VILT CPQY PGSE ILWQ HNDK NIGG DEDD KNIG SDED HLSL KEFS ELEQ SGYY VCYP RGSK PEDA NFYL YLRA RVCE NCME MD |
Tested Applications: | WB IHC-P IF/ICC IP FC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | T3E; TCRE; IMD18; CD3epsilon; CD3E |
Positive Sample: | Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 23kDa |
Observed MW: | 23kDa |
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Purification Method: | Affinity purification |
Gene ID: | 916 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |