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CD3E Monoclonal Antibody [PAT3H3AT] (CPAB0342)

SKU:
CPAB0342
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT3H3AT
Applications:
WB
ELISA
€149
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Description

system_update_alt Datasheet

CD3E Monoclonal Antibody [PAT3H3AT] (CPAB0342)

The CD3e Monoclonal Antibody (CPAB0342) is a valuable tool for research involving the CD3e protein, a key component of the T-cell receptor complex. This antibody, produced in vitro, is highly specific to CD3e and has been validated for use in various applications, including flow cytometry and immunohistochemistry.CD3e is essential for T-cell activation and function, making this antibody particularly useful for studying T-cell development, activation, and function in both normal and diseased states. Its high specificity and sensitivity allow for accurate detection and analysis of CD3e expression in various cell types, making it an ideal choice for research in immunology, cancer biology, and autoimmune diseases.

By targeting CD3e, researchers can gain valuable insights into the role of T-cells in immune responses and diseases, paving the way for the development of novel therapies and diagnostic tools. Whether studying immune cell signaling pathways or investigating T-cell-mediated diseases, the CD3e Monoclonal Antibody is a crucial tool for advancing our understanding of T-cell biology.

Product Name:CD3E Antibody
Product Sku:CPAB0342
Size:5μg
Host Species:Mouse
Immunogen:Anti-human CD3E mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CD3E protein 23-126 amino acids purified from Ecoli.
Clone:PAT3H3AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:CD3E antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1
Background:CD3-epsilonpolypeptide (CD3E) along with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, creates the T-cell receptor-CD3 complex. This complex has an imperative role in coupling antigen recognition to a number of intracellular signal-transduction pathways. The genes encoding the epsilon, gamma delta polypeptides are found in the same cluster on chromosome 11. The epsilon polypeptide plays a vital role in T-cell development. CD3E gene defects cause immunodeficiency. CD3E is also linked to a susceptibility to type I diabetes in women.
Synonyms:T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, T3E, TCRE.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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