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CD36/SR-B3 Rabbit Polyclonal Antibody (CAB5792)

SKU:
CAB5792
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:CD36/SR-B3 Rabbit Polyclonal Antibody
SKU:CAB5792
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 30-439 of human CD36/SR-B3 (NP_000063.2).
Sequence:GDLL IQKT IKKQ VVLE EGTI AFKN WVKT GTEV YRQF WIFD VQNP QEVM MNSS NIQV KQRG PYTY RVRF LAKE NVTQ DAED NTVS FLQP NGAI FEPS LSVG TEAD NFTV LNLA VAAA SHIY QNQF VQMI LNSL INKS KSSM FQVR TLRE LLWG YRDP FLSL VPYP VTTT VGLF YPYN NTAD GVYK VFNG KDNI SKVA IIDT YKGK RNLS YWES HCDM INGT DAAS FPPF VEKS QVLQ FFSS DICR SIYA VFES DVNL KGIP VYRF VLPS KAFA SPVE NPDN YCFC TEKI ISKN CTSY GVLD ISKC KEGR PVYI SLPH FLYA SPDV SEPI DGLN PNEE EHRT YLDI EPIT GFTL QFAK RLQV NLLV KPSE KIQV LKNL KRNY IVPI LWLN ETGT IGDE KANM FRSQ VTGK IN
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:1000 - 1:5000 IHC-P,1:100 - 1:500 IF/ICC,1:50 - 1:200
Synonyms:FAT; GP4; GP3B; GPIV; CHDS7; PASIV; SCARB3; BDPLT10; CD36/SR-B3
Positive Sample:Mouse heart,Rat heart
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Multi-pass membrane protein.
Calculated MW:53kDa
Observed MW:70-110kDa

The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene.

Purification Method:Affinity purification
Gene ID:948
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using CD36/SR-B3 Rabbit pAb (CAB5792) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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