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CD33 Polyclonal Antibody

SKU:
CAB21714
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€139 - €529
Frequently bought together:

Description

CD33 Polyclonal Antibody (CAB21714)

The CD33 Polyclonal Antibody is a valuable tool for researchers studying CD33, a cell surface molecule with important implications in immunology and cancer research. This antibody, produced in rabbits, is specifically designed to detect and analyze the CD33 protein in human samples using Western blot techniques. By targeting CD33, researchers can gain insights into immune regulation and potential therapeutic targets for diseases like cancer and autoimmune disorders.

CD33 is a known marker of hematopoietic stem cells and myeloid lineage cells, making it a key player in immune function and hematopoiesis. Its involvement in various diseases, including acute myeloid leukemia (AML), makes it an attractive target for further investigation. The CD33 Polyclonal Antibody provides a reliable tool for researchers seeking to better understand the role of CD33 in disease pathogenesis and potential therapeutic interventions.

Product Name:CD33 Polyclonal Antibody
Product Code:CAB21714
Reactivity:Human
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Positive Samples:HeLa
Cellular Location:Cell membrane, Single-pass type I membrane protein

Enables protein phosphatase binding activity and sialic acid binding activity. Involved in several processes, including negative regulation of cytokine production; negative regulation of monocyte activation; and positive regulation of protein tyrosine phosphatase activity. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and peroxisome.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 49-259 of human CD33 (NP_001763.3).
Sequence:YYDKN SPVHG YWFRE GAIIS RDSPV ATNKL DQEVQ EETQG RFRLL GDPSR NNCSL SIVDA RRRDN GSYFF RMERG STKYS YKSPQ LSVHV TDLTH RPKIL IPGTL EPGHS KNLTC SVSWA CEQGT PPIFS WLSAA PTSLG PRTTH SSVLI ITPRP QDHGT NLTCQ VKFAG AGVTT ERTIQ LNVTY VPQNP TTGIF PGDGS GKQET RAGVV H
Synonyms:p67, SIGLEC3, SIGLEC-3
Calculated MW:40kDa
Observed MW:67kDa

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