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APC Anti-Human CD33 Antibody [6C5] (AGEL2847)

SKU:
AGEL2847
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
6C5
Conjugation:
APC
€169 - €579
Frequently bought together:

Description

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APC Anti-Human CD33 Antibody [6C5]

The APC Anti-Human CD33 Antibody (6C5), available from www.assaygenie.com, is a highly specific and sensitive tool for research involving the CD33 cell surface molecule. CD33 is a myeloid lineage-specific transmembrane receptor that plays a crucial role in the regulation of myeloid cell proliferation and differentiation.This monoclonal antibody, generated using innovative technology, is specifically designed to target the CD33 protein in human samples. It is optimized for applications such as flow cytometry, immunohistochemistry, and immunofluorescence, allowing for precise detection and analysis of CD33 expression in various cell types, including myeloid-derived suppressor cells.

The APC Anti-Human CD33 Antibody (6C5) holds great potential for research in immunology, hematology, and oncology. It enables scientists to explore the role of CD33 in hematopoiesis, immune response modulation, and its implications in diseases such as acute myeloid leukemia (AML) where aberrant CD33 expression is often observed. By providing a reliable tool for CD33 detection and characterization, this antibody contributes to advancing our understanding of myeloid cell biology and holds promise for the development of targeted therapies in related disorders.

Product Title:APC Anti-Human CD33 Antibody [6C5]
SKU:AGEL2847
Size:20 Tests, 100 Tests, 200 Tests
Clone No:6C5
Synonyms:Myeloid cell surface antigen CD33;CD33;Sialic acid-binding Ig-like lectin 3;Siglec-3;gp67;SIGLEC3;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P20138
Gene ID:945
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD33 is a 67 kD type I transmembrane glycoprotein also known as Siglec-3, gp67, and p67. It is a sialoadhesion immunoglobulin superfamily member expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. CD33 is absent on normal platelets, lymphocytes, erythrocytes and hematopoietic stem cells. CD33 functions as a sialic acid-dependent cell adhesion molecule with carbohydrate/lectin binding activity.

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