The CD31/PECAM1 Rabbit Monoclonal Antibody (CAB4900) is a highly specific antibody designed for research involving CD31/PECAM1, a cell surface molecule known for its role in cell adhesion and signaling. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications, including immunohistochemistry, flow cytometry, and Western blotting.CD31/PECAM1 is involved in various physiological processes, including angiogenesis, inflammation, and immune response regulation. Its expression on endothelial cells and leukocytes makes it a valuable marker for studying vascular biology and immune cell interactions in health and disease.
This antibody enables precise detection and analysis of CD31/PECAM1 expression in different tissue types, allowing researchers to explore its functions in cardiovascular disorders, inflammatory diseases, and cancer progression.Overall, the CD31/PECAM1 Rabbit Monoclonal Antibody (CAB4900) is an essential tool for investigating the roles of CD31/PECAM1 in various biological processes and diseases, contributing to the advancement of research in vascular biology, immunology, and oncology.
Product Name:
CD31/PECAM1 Rabbit Monoclonal Antibody
SKU:
CAB4900
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 630-738 of CD31/PECAM1 (NP_000433.4).
Cell junction, Cell junction, Cell membrane, Lipid-anchor, Single-pass type I membrane protein.
Calculated MW:
83kDa
Observed MW:
130-140kDa
The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.
Purification Method:
Affinity purification
Gene ID:
5175
Clone Number:
ARC50355
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CD31/PECAM1 Rabbit mAb (CAB4900) at 1:10000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
