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CD31 Biotin Monoclonal Antibody [hCD31] (CPAB0297)

SKU:
CPAB0297
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
hCD31
Applications:
IHC
FC
€660
Frequently bought together:

Description

system_update_alt Datasheet

CD31 Biotin Monoclonal Antibody [hCD31] (CPAB0297)

The CD31 Biotin Antibody (CPAB0297) is a high-quality research tool designed for the detection and analysis of CD31, a cell surface molecule known for its involvement in various cellular processes, including inflammation and angiogenesis. This polyclonal antibody, produced in rabbits, exhibits strong reactivity with human samples and is validated for use in a variety of applications, including immunohistochemistry and flow cytometry.CD31, also referred to as platelet endothelial cell adhesion molecule-1 (PECAM-1), is a key player in the regulation of endothelial cell function and vascular integrity. Its role in mediating cell-cell adhesion and signaling makes it a promising target for studies in cardiovascular biology, vascular disease, and cancer research.

The CD31 Biotin Antibody enables precise visualization and quantification of CD31 expression in tissues and cells, facilitating a better understanding of its physiological and pathological functions.Researchers working in the fields of vascular biology, immunology, and oncology can benefit from the versatility and specificity of the CD31 Biotin Antibody. By elucidating the complex mechanisms involving CD31, novel therapeutic strategies for cardiovascular disorders, inflammatory diseases, and cancer progression can be developed. Invest in this reliable antibody to advance your research and uncover new insights into the role of CD31 in health and disease.

Product Name:CD31 Biotin Antibody
Product Sku:CPAB0297
Size:500μg
Host Species:mouse
Immunogen:Enriched human platelets
Clone:hCD31
Reactivity:Human
Applications:Immunohistochemistry, Flow Cytometry
Purification Method:Protein A
Isotype:IgG1
Background:CD31 is a glycoprotein expressed on endothelial cells, platelets, macrophages and Kupffer cells, granulocytes, T / NK cells, lymphocytes, megakaryocytes, fibroblasts, osteoclasts, neutrophils. In humans, the gene encoding CD31 is found on chromosome 17. CD31 is a cluster of differentiation molecule. It is also called PECAM-1 for platelet endothelial cell adhesion molecule. It plays a key role in removing aged neutrophils from the body. Both the neutrophil and the macrophage express CD31 on their membranes, and during the testing process, these CD31 molecules bind the two cells together. If the neutrophil is healthy, it will send a signal to the macrophage, and the CD31 molecules will detach. CD31 is also expressed in certain tumors, including epithelioid hemangioendothelioma, epithelioid sarcoma-like hemangioendothelioma, other vascular tumors, histiocytic malignancies, and plasmacytomas. It is rarely found in some sarcomas and carcinomas.
Synonyms:Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA', CD31 antigen, PECAM1, CD31.
Storage Buffer:In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

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