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CD31 Monoclonal Antibody [hCD31] (CPAB0295)

SKU:
CPAB0295
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
hCD31
Applications:
IHC
FC
€660
Frequently bought together:

Description

system_update_alt Datasheet

CD31 Monoclonal Antibody [hCD31] (CPAB0295)

The CD31 Polyclonal Antibody (CPAB0295) is a powerful tool for researchers studying CD31, a cell surface protein involved in various biological processes such as cell adhesion, migration, and angiogenesis. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for Western blot applications.CD31, also known as platelet endothelial cell adhesion molecule-1 (PECAM-1), is a crucial molecule in vascular biology, playing a key role in endothelial cell function and vascular integrity. Its expression is commonly used as a marker for endothelial cells, making this antibody an excellent choice for studies related to cardiovascular disease, angiogenesis, and inflammation.

By targeting the CD31 protein, researchers can gain valuable insights into the molecular mechanisms underlying endothelial cell behavior and vascular function. This antibody's versatility and specificity make it an essential tool for investigations in vascular biology, cancer research, and immunology. Unlock the potential of CD31 with the CPAB0295 Polyclonal Antibody from Assay Genie.

Product Name:CD31 Antibody
Product Sku:CPAB0295
Size:500μg
Host Species:mouse
Immunogen:Enriched human platelets
Clone:hCD31
Reactivity:Human
Applications:Immunohistochemistry, Flow Cytometry
Purification Method:Protein A
Isotype:IgG1
Background:CD31 is a glycoprotein expressed on endothelial cells, platelets, macrophages and Kupffer cells, granulocytes, T / NK cells, lymphocytes, megakaryocytes, fibroblasts, osteoclasts, neutrophils. In humans, the gene encoding CD31 is found on chromosome 17. CD31 is a cluster of differentiation molecule. It is also called PECAM-1 for platelet endothelial cell adhesion molecule. It plays a key role in removing aged neutrophils from the body. Both the neutrophil and the macrophage express CD31 on their membranes, and during the testing process, these CD31 molecules bind the two cells together. If the neutrophil is healthy, it will send a signal to the macrophage, and the CD31 molecules will detach. CD31 is also expressed in certain tumors, including epithelioid hemangioendothelioma, epithelioid sarcoma-like hemangioendothelioma, other vascular tumors, histiocytic malignancies, and plasmacytomas. It is rarely found in some sarcomas and carcinomas.
Synonyms:Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA', CD31 antigen, PECAM1, CD31.
Storage Buffer:In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

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