The CD302 Polyclonal Antibody (PAC02309) is a valuable tool for researchers studying CD302, a cell surface molecule with potential implications in immune regulation. Raised in rabbits, this antibody is highly specific for human samples and is recommended for use in Western blot applications. By binding to the CD302 protein, researchers can easily detect and analyze this molecule in a variety of cell types, making it an essential component for immunology and cancer research studies.CD302, also known as an immune regulatory protein, is believed to play a key role in immune system function by potentially inhibiting immune responses.
Understanding the functions of CD302 may provide insights into immune homeostasis, inflammation regulation, and the modulation of allergic reactions. Researchers are particularly interested in studying CD302 in the context of diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions, in hopes of uncovering new therapeutic targets and treatment strategies. By utilizing the CD302 Polyclonal Antibody, researchers can further explore the role of this molecule in immune regulation and potentially develop novel approaches for managing immune-related diseases.
Synthesized peptide derived from internal of human CD302.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HT-29 cells, using CD302 antibody.
Immunohistochemistry analysis of paraffin-embedded human lymph node tissue using CD302 antibody.
Background:
Potential multifunctional C-type lectin receptor that may play roles in endocytosis and phagocytosis as well as in cell adhesion and migration.
Synonyms:
CD302 antigen [Precursor]; C-type lectin domain family 13 member A; C-type lectin BIMLEC; Type I transmembrane C-type lectin receptor DCL-1; CD302
UniProt Protein Function:
CD302: Potential multifunctional C-type lectin receptor that may play roles in endocytosis and phagocytosis as well as in cell adhesion and migration. 5 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 2q24.2Cellular Component: cell cortex; filopodium; membraneBiological Process: phagocytosis
UniProt Protein Details:
NCBI Summary:
CD302 is a C-type lectin receptor involved in cell adhesion and migration, as well as endocytosis and phagocytosis (Kato et al., 2007 [PubMed 17947679]).[supplied by OMIM, Aug 2008]
