The CD302 Polyclonal Antibody (PACO2148) is specifically designed for research involving the CD302 protein, a cell surface molecule implicated in immune regulation. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. It binds to the CD302 protein, allowing for detection and analysis in various cell types, making it ideal for studies in immunology and cancer research.CD302, also known as an immune inhibitory receptor, plays a crucial role in immune homeostasis by regulating inflammation and inhibiting allergic reactions.
Its importance in immune response modulation makes it a valuable target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of CD302 is essential for developing therapies that can harness or modulate immune function in these disease contexts.
Antibody Name:
CD302 Antibody
Antibody SKU:
PACO02148
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human DCL-1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
CD302; CLEC13A; DCL1; KIAA0022; CD302 antigen; C-type lectin BIMLEC; C-type lectin domain family 13 member A; DEC205-associated C-type lectin 1; Type I transmembrane C-type lectin receptor DCL-1; CD302
UniProt Protein Function:
CD302: Potential multifunctional C-type lectin receptor that may play roles in endocytosis and phagocytosis as well as in cell adhesion and migration. 5 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 2q24.2Cellular Component: cell cortex; filopodium; membraneBiological Process: phagocytosis
UniProt Protein Details:
NCBI Summary:
CD302 is a C-type lectin receptor involved in cell adhesion and migration, as well as endocytosis and phagocytosis (Kato et al., 2007 [PubMed 17947679]).[supplied by OMIM, Aug 2008]
