The CD300C Polyclonal Antibody (CAB10420) is a valuable tool for researchers studying the CD300C protein, a cell surface molecule with implications in immune regulation. This antibody, generated in rabbits, exhibits high reactivity specifically with human samples and has been validated for Western blot applications. By binding to the CD300C protein, this antibody enables the detection and analysis of CD300C in a variety of cell types, making it an ideal choice for studies in immunology and cancer research.CD300C, also referred to as an immune inhibitory receptor, plays a crucial role in maintaining immune homeostasis by modulating inflammation and inhibiting allergic responses.
Its involvement in immune response regulation makes CD300C an important target for investigations into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of CD300C is essential for the development of therapies that can either harness or modulate immune responses in these disease contexts.
Product Name:
CD300C Rabbit Polyclonal Antibody
SKU:
CAB10420
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-183 of human CD300C (NP_006669.1).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
25kDa
Observed MW:
52kDa
The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes (Jackson et al., 1992 [PubMed 1349532]).
Purification Method:
Affinity purification
Gene ID:
10871
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CD300C antibody (CAB10420) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
