The CD2BP2 Polyclonal Antibody (CAB15777) is a valuable tool for researchers studying the cell surface molecule CD2BP2, which is involved in immune regulation and cell signaling pathways. This antibody, produced through rabbit immunization, has high specificity for human samples and has been validated for use in Western blotting applications.CD2BP2, also known as CD2 binding protein 2, is a crucial player in immune responses and has been implicated in various diseases, including cancer and autoimmune disorders. By binding to the CD2BP2 protein, this polyclonal antibody enables researchers to detect and analyze its expression in different cell types, providing valuable insights for studies in immunology and cancer research.
Understanding the role of CD2BP2 in immune regulation and disease pathogenesis is essential for developing targeted therapies and treatment strategies. With its high reactivity and specificity, the CD2BP2 Polyclonal Antibody is a reliable tool for investigating the functions and mechanisms of CD2BP2 in various biological contexts.
Product Name:
CD2BP2 Rabbit Polyclonal Antibody
SKU:
CAB15777
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-341 of human CD2BP2 (NP_006101.1).
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.
Purification Method:
Affinity purification
Gene ID:
10421
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CD2BP2 Rabbit pAb (CAB15777) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
