The CD2AP Polyclonal Antibody (CAB7788) is a valuable tool for researchers studying CD2-associated protein (CD2AP), which plays a crucial role in cell signaling and immune response regulation. This antibody, generated in rabbits, demonstrates high specificity and reactivity towards human samples, making it ideal for use in Western blot applications.CD2AP is known for its involvement in cell adhesion, T-cell activation, and immune receptor signaling pathways. By targeting the CD2AP protein, this antibody enables researchers to detect and analyze protein expression in various cell types, shedding light on its functions in immunology and cancer research.
The CD2AP Polyclonal Antibody holds great potential for advancing our understanding of cellular processes and diseases linked to CD2AP dysregulation, such as autoimmune disorders, infectious diseases, and cancer. By investigating the role of CD2AP in immune regulation and signaling, researchers can potentially develop targeted therapies to modulate immune responses in various pathological conditions.
Product Name:
CD2AP Rabbit Polyclonal Antibody
SKU:
CAB7788
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 360-639 of human CD2AP (NP_036252.1).
This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
Purification Method:
Affinity purification
Gene ID:
23607
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CD2AP Rabbit pAb (CAB7788) at 1:500 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 60s.
