null

CD29 Monoclonal Antibody [Pk2D5AT] (CPAB0336)

SKU:
CPAB0336
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
Pk2D5AT
Applications:
WB
ELISA
$179
Frequently bought together:

Description

system_update_alt Datasheet

CD29 Monoclonal Antibody [Pk2D5AT] (CPAB0336)

The CD29 Monoclonal Antibody (CPAB0336) is a valuable tool for research involving CD29, also known as integrin beta-1, a cell surface protein involved in cell adhesion and signaling processes. This antibody, generated in mice, is highly specific to CD29 in human samples and has been validated for use in various applications, including Western blot and immunofluorescence.CD29 is a key player in cell adhesion, migration, and signal transduction, making it essential for processes like wound healing, tissue remodeling, and immune response. Its role in cancer progression and metastasis also makes it a promising target for therapeutic interventions.

The CD29 Monoclonal Antibody allows for precise detection and analysis of CD29 expression in different cell types, providing valuable insights for studies in cell biology, cancer research, and immunology.By understanding the functions and regulation of CD29, researchers can gain valuable insights into processes like cell proliferation, differentiation, and invasion. The CD29 Monoclonal Antibody offers a reliable tool for investigating the role of CD29 in various physiological and pathological conditions, paving the way for the development of targeted therapies and diagnostic strategies in cancer and other diseases.

Product Name:CD29 Antibody
Product Sku:CPAB0336
Size:5μg
Host Species:Mouse
Immunogen:Anti-human CD29 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CD29 amino acids 34-141 purified from Ecoli.
Clone:Pk2D5AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:CD29 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:Integrin beta 1, also known as CD29, is a 130 kDa transmembrane glycoprotein that forms noncovalent complexes with various Integrin alpha subunits (including alpha 1, alpha 2, alpha 3, alpha 4, alpha 5, and alpha 6, also known as CD49a, CD49b, CD49c, CD49d, CD49e, and CD49f, respectively) to form the functional receptors that bind to specific extracellular matrix proteins. Integrin receptors are involved in the regulation of a variety of important biological functions, including embryonic development, wound repair, hemostasis, and prevention of programmed cell death. They are also implicated in abnormal pathological states such as tumor directed angiogenesis, tumor cell growth, and metastasis. These heterodimeric receptors bridge the cytoplasmic actin cytoskeleton with proteins present in the extracellular matrix and/or on adjacent cells. The clustering of integrins on a cell surface leads to the formation of focal contacts. Interactions between integrins and the extracellular matrix l
Synonyms:Integrin beta-1, Fibronectin receptor subunit beta, Integrin VLA-4 subunit beta, CD29 antigen, ITGB1, CD29, FNRB, MDF2, VLAB, GPIIA, MSK12.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

Related Products